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  Talk Python : youtube
02  october     00h12
Tachyon, Python 3.15’s Built-in Sampling Profiler - Talk Python to Me Ep. 565
   Do you know what’s actually slow in your Python app? Or are you guessing? Until now, profiling Python meant a tracing profiler that made your code 2...
22  september     18h35
EVE Online Departs for Python 3 - Talk Python to Me Ep. 564
   Every ship in EVE Online eventually undocks and leaves the station. This time, it’s the whole game. EVE has run on Python 2 since it launched in 2003...
16  september     17h02
Getting Started with Rust as Python Devs - Talk Python to Me Ep. 563
   Lint the entire CPython code base from scratch. It takes 0.3 seconds. Three blinks of an eye.That is ruff, and it is written in Rust. So are Pydantic...
10  september     15h05
DuckLake: The Lakehouse That’s Just SQL and Parquet - Talk Python to Me Ep. 562
   How many files does your query read before it reads any data? On some data lakes, you go through JSON and metadata files first, just to learn which...
08  september     14h58
12 Things You Should (and Shouldn’t) Do in AWS - Talk Python to Me Ep. 559
   Your site is down. It’s 3am. Is it a bug, a bill, or a breach? You can’t tell yet, and everyone is watching you find out. Matt Lea has spent fifteen...
04  september     07h29
TonIO, a Multi-threaded Async Runtime for Python - Talk Python to Me Ep. 561
   How many cores does your machine have, 10, 18? Your async Python code uses just one of them. That isn’t a bug in asyncio. That’s the design, and...
27  august     04h34
Building a Research OS: From Django to 30,000 Samples - Talk Python to Me Ep. 560
   In 2020, a gastroenterologist in Glasgow did the math on his new research study and came up with 30,000 samples, arriving over two years from three...
16  july     11h03
Hyper-Personal Software with Python - Talk Python to Me Ep. 558
   Every company has one. The little internal tool that Jane built back in 2021, and then Jane left. Nobody understands it, nobody will touch it. There...
07  july     05h31
Security of everything at PyCon 2026 - Talk Python to Me Ep. 557
   Security has always been the vegetables of software. Everyone agrees it matters, and somehow it never quite makes it onto the plate. At PyCon US this...
03  july     03h50
Updates on Django’s Async Story - Talk Python to Me Ep. 556
   For years, "Django and async" came with an asterisk. The docs themselves warned you off it. Scary performance notes, a story that felt half...
01  july     06h23
Marimo Pair - A Canvas for Agent Developers Collaboration - Talk Python to Me Ep. 555
   Coding agents have gotten really good at one kind of work. You scope a feature, edit some files, run the tests, ship it. It all happens on disk. But...
26  june     08h23
Trustworthy AI in Healthcare and Longevity - Talk Python to Me Ep. 554
   You ask an AI a question and it answers with total confidence. Most of the time, a confidently wrong answer is just an annoyance. But what if the...
23  may     03h41
AI Contributions and Maintainer Load in Open Source - Talk Python to Me Ep. 550
   You wake up, brew the coffee, open GitHub, and there it is. Another pull request on your open source project. Thirteen thousand lines added. No issue...
20  may     03h56
Great Docs - Talk Python to Me Ep. 549
   Your documentation has two audiences now - humans reading the rendered HTML, and AI agents trying to make sense of your library. Rich Iannone and...
06  may     08h55
Event Sourcing Design Pattern - Talk Python to Me Ep. 548
   What if your database worked more like Git? Every change captured as an immutable event you can replay, instead of a single mutating row that quietly...
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